Allergan, Inc
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Allergan, Inc. was an American global
pharmaceutical A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and re ...
company focused on eye care, neurosciences, medical dermatology,
medical aesthetics Aesthetic medicine is a broad term for specialties that focus on altering cosmetic appearance through the treatment of conditions including scars, skin laxity, wrinkles, moles, liver spots, excess fat, cellulite, unwanted hair, skin discoloration, ...
, breast enhancement, obesity intervention and urologics. Allergan, Inc. was formed in 1948, incorporated in 1950 and became a public company in 1970. It ceased operation in 2015 when it was acquired by Irish-based
Actavis plc Actavis Generics (formerly known as Watson Pharmaceuticals and Actavis plc, prior to the acquisition of Irish-based Allergan Inc) is a global pharmaceutical company focused on acquiring, developing, manufacturing and marketing branded pharmaceuti ...
(itself a 2013 U.S.
tax inversion A tax inversion or corporate tax inversion is a form of tax avoidance where a corporation restructures so that the current parent is replaced by a foreign parent, and the original parent company becomes a subsidiary of the foreign parent, thus mov ...
to Ireland), who then renamed the group as
Allergan plc Allergan plc is an American, Irish-domiciled pharmaceutical company that acquires, develops, manufactures and markets brand name drugs and medical devices in the areas of medical aesthetics, eye care, central nervous system, and gastroenterology. ...
.


Early history

The company traces its roots back to 1948 and pharmacist Gavin S. Herbert, who in 1950 established Allergan Pharmaceuticals, Inc. Allergan focused on the discovery and development of novel formulations for specialty markets, as well as intimate collaboration with physicians and the scientific community. 1953 saw Allergan producing eye drops and formulating new products such as the first cortisone eye drop to treat allergic inflammation and the first ophthalmic steroid decongestant.


Acquisitions

Allergan became a publicly traded company in 1970 and was acquired by
SmithKline GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tent ...
for $259 million in 1980. After generating $756 million in revenue and $80 million in profit in 1988, Allergan was spun-off by SmithKline Beckman in 1989. In July 2002, the Allergan ophthalmic surgical and contact lens care businesses were spun-off to create a new company, Advanced Medical Optics. In 2003, Allergan's flagship product,
Botox Botulinum toxin, or botulinum neurotoxin (BoNT), is a neurotoxic protein produced by the bacterium '' Clostridium botulinum'' and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromus ...
, was the focus of a high-profile lawsuit and media scrutiny. In March 2006, Allergan acquired Inamed Corporation for $3 billion. On March 1, 2013, the company acquired MAP Pharmaceuticals Inc., a development-stage company mainly researching the treatment of
migraine Migraine (, ) is a common neurological disorder characterized by recurrent headaches. Typically, the associated headache affects one side of the head, is pulsating in nature, may be moderate to severe in intensity, and could last from a few hou ...
and other oral drugs in Neurology for approximately $958 million. The principal products of this sub-company are under review with the US
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
(FDA). In December 2013, the company sold its obesity intervention business to Apollo Endosurgery, Inc., for a cash payment of $75 million and a $15 million minority equity interest in Apollo Endosurgery. In November 2014,
Actavis Actavis Generics (formerly known as Watson Pharmaceuticals and Actavis plc, prior to the acquisition of Irish-based Allergan, Inc., Allergan Inc) is a global pharmaceutical company focused on acquiring, developing, manufacturing and marketing bran ...
announced its intention to acquire Allergan, Inc., the manufacturer of Botox Completion of the deal would increase its market capitalization to $147 billion. On March 17, 2015,
Actavis Actavis Generics (formerly known as Watson Pharmaceuticals and Actavis plc, prior to the acquisition of Irish-based Allergan, Inc., Allergan Inc) is a global pharmaceutical company focused on acquiring, developing, manufacturing and marketing bran ...
completed the acquisition of Allergan, Inc. in a cash and equity transaction valued at approximately $70.5 billion, and the latter was folded into Actavis. The combination created a $23 billion diversified global pharmaceutical company with commercial reach across 100 countries. In June 2015,
Actavis Actavis Generics (formerly known as Watson Pharmaceuticals and Actavis plc, prior to the acquisition of Irish-based Allergan, Inc., Allergan Inc) is a global pharmaceutical company focused on acquiring, developing, manufacturing and marketing bran ...
officially changed its name to
Allergan, plc Allergan plc is an American, Irish-domiciled pharmaceutical company that acquires, develops, manufactures and markets brand name drugs and medical devices in the areas of medical aesthetics, eye care, central nervous system, and gastroenterology. ...
. In June, Allergan, Inc. announced it would acquire Kythera Biopharmaceuticals for around $2.1 billion.


Attempted acquisition by Valeant Pharmaceuticals

On April 22, 2014, details were released by
Valeant Pharmaceuticals Bausch Health Companies Inc. (formerly Valeant Pharmaceuticals International, Inc.) is a Canadian multinational specialty pharmaceutical company based in Laval, Quebec, Canada. It develops, manufactures and markets pharmaceutical products and ...
and hedge fund CEO,
Bill Ackman William Albert Ackman (born May 11, 1966) is an American billionaire investor and hedge fund manager. He is the founder and CEO of Pershing Square Capital Management, a hedge fund management company. His investment approach makes him an activis ...
, about a $46 billion (CAD) offer presented to Allergan. Valeant proposed to exchange $48.30 in cash and 0.83 shares of Valeant per Allergan share. Allergan, Inc. stockholders would own 43 per cent of the combined company. This bid was rejected by Allergan as being too risky, claiming Valeant's business model of serial acquisitions and low organic growth being unsustainable. Soon after Valeant released a statement saying a new offer will be presented May 28, 2014, where it emerged that Valeant had increased their offer to $49.4 billion. On May 31 the offer was revised and increased to $53.3 billion. On June 18, Valeant began its tender offer for a hostile takeover of Allergan. On August 27, 2014, Valeant and
Pershing Square Capital Management Pershing Square Capital Management is an American hedge fund management company founded and run by Bill Ackman, headquartered in New York City. Company history In 2004, with $54 million in funding from his personal funds and former business part ...
asked a Chancery Judge to set a trial for September 24, 2014 to decide on whether Valeant and Pershing had properly secured enough support from Allergan shareholders to force a meeting of investors to consider replacing a majority of the company's directors. On the same day Allergan announced that they had set a December shareholder vote to decide whether the company should replace part of the board of directors. In the afternoon of August 27, ''Bloomberg'' reported that Valeant and Pershing Square had won their case with the Chancery Judge setting an October 6 date for the aforementioned trial. On November 17, 2014, Actavis, plc announced it would acquire
Allergan Allergan plc is an American, Irish-domiciled pharmaceutical company that acquires, develops, manufactures and markets brand name drugs and medical devices in the areas of medical aesthetics, eye care, central nervous system, and gastroenterology. ...
in a white knight bid for approximately $66 billion, putting an end to Valeant's hostile takeover attempt.


Company Structure


Safety reports

In 2011, FDA reported issues in the investigation of safety of silicone gel-filled breast implants. However, the company announced later the reassurance to patients of the safety and exclusion of its drugs from the investigated breast implant devices, stating that all of its products are above safety standards around the world.


References


External links


Allergan website

Allergan foundation
{{Authority control Companies formerly listed on the New York Stock Exchange Companies based in Irvine, California Defunct pharmaceutical companies of the United States Pharmaceutical companies established in 1948 Pharmaceutical companies disestablished in 2015 Health care companies based in California Life sciences industry 2015 mergers and acquisitions